Cannabinoids, endocannabinoids, and cancer
نویسندگان
چکیده
منابع مشابه
Cancer therapy-The role of cannabinoids and endocannabinoids
Cannabinoids have recently been added to the therapeutic armamentarium of cancer, not only for their palliative effects (inhibition of chemotherapy-induced nausea and vomiting) but also as antitumor drugs, based on their ability to induce cancer cell apoptosis and reduce neoangiogenesis as well as tumor cell invasiveness and metastasis. A large number of researches have reported the antitumor e...
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Since the identification of cannabinoid receptors in the 1990s, a research field has been dedicated to exploring the role of the cannabinoid system in immunity and the inflammatory response in human tissues and animal models. Although the cannabinoid system is present and crucial in many human tissues, studying the impact of cannabinoids on the lungs is particularly relevant because of their co...
متن کاملEndocannabinoids and Cancer.
A large body of evidence shows that cannabinoids, in addition to their well-known palliative effects on some cancer-associated symptoms, can reduce tumour growth in animal models of cancer. They do so by modulating key cell signalling pathways involved in the control of cancer cell proliferation and survival. In addition, cannabinoids inhibit angiogenesis and cell proliferation in different typ...
متن کاملCannabinoids and cancer.
Marijuana has been used in medicine for millennia, but it was not until 1964 that delta9-tetrahydrocannabinol (delta9-THC), its major psychoactive component, was isolated in pure form and its structure was elucidated. Shortly thereafter it was synthesized and became readily available. However, it took another decade until the first report on its antineoplastic activity appeared. In 1975, Munson...
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Cannabinoids-endocannaboids are possible preventatives of common diseases including cancers. Cannabinoid receptors (CB(½), TRPV1) are central components of the system. Many disease-ameliorating effects of cannabinoids-endocannabinoids are receptor mediated, but many are not, indicating non-CBR signaling pathways. Cannabinoids-endocannabinoids are anti-inflammatory, anti-proliferative, anti-inva...
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ژورنال
عنوان ژورنال: Cancer and Metastasis Reviews
سال: 2011
ISSN: 0167-7659,1573-7233
DOI: 10.1007/s10555-011-9318-8